Arthur J. Cain is an evolutionary biologist whose research interests have included genetics, natural selection, biogeography, and systematics. Based at Oxford University and, later, the University of Liverpool, much of Cain's research was field-based, focusing on terrestrial gatsropods. This collection contains correspondence, grant applications, reports, programs for scientific meetings, unpublished papers and lectures, research notes, charts, graphs, maps, and manuscript reviews of journal articles and books. The Cain Papers is divided into three series: I. Correspondence ; II. Subject Files ; and, III. Papers by Colleagues. Arrangement is alphabetical by folder title, and chronological within each folder.

A geneticist and educator, Philip Macdonald Sheppard was head of the Department of Genetics at the University of Liverpool from 1963-1976. His research centered on polymorphism, mimicry, blood groups, genetic disease, and speciation, using a variety of subjects, including the gastropod Cepaea nemoralis, butterflies, and humans. He may be best remembered for his classic study of industrial melanism in the pepper moth Biston betularia. The Sheppard Papers (1911-1983; bulk dates, 1940-76) contain correspondence, subject files, notes, and manuscripts that document Sheppard's life as a geneticist. The earliest piece in the collection is a lepidopterist's notebook from 1911, possibly J. R. Hobhouse's, however the bulk dates from 1940 to 1976, Sheppard's most productive and influential years. Among other things, these materials document Sheppard's research on the Scarlet Tiger moth, swallowtail butterflies, and ABO blood groups in humans, as well as his position as head of the Department of Genetics at the University of Liverpool.